April 24, 2014

Summer 2010 Thematic Program on the Mathematics of Drug Resistance in Infectious Diseases

July 5-16, 2010
Theme Weeks and Workshop on Emergence and Spread of Drug Resistance
held at Fields Institute, 222 College St. (map)

Headed by:
David Fisman (University of Toronto)
Troy Day (Queen’s)
Jianhong Wu (York)
Shigui Ruan (Miami)
Seyed M. Moghadas (National Research Council)
Tom Wong (Public Health Agency of Canada)

Partners: Ontario Agency for Health Protection and Promotion

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Outline of the Program

This two week block will open the thematic program, and will focus on introducing the mathematics of drug resistance, highlighting current modeling challenges and unresolved issues.

Monday July 5
9:30 -12:00 Long-term Program researchers check in with Fields Members Liaison Room 330 at Fields
12:00-1:00 Registration on-site
1:00-2:30 Marc Lipsitch: "How is coexistence between drug-susceptible and -resistant bacteria maintained"
3:00-3:30 Alison McGeer: "Antiviral resistance and influenza"
Opening reception @ 5:00 pm
Tuesday July 6
9:30-10:00 Sylvain Gandon: "Evolutionary epidemiology of drug-resistance in space"
10:00-10:30 Nick Daneman: "Facile Solutions for a [Clostridium] difficile Problem"
Reference 1
Reference 2
Reference 3
Reference 4
10:30-11:00 Break
11:00-11:30 Erika D'Agata: "TBA"
11:30-12:00 Tim Reluga: "Linear models of antibiotic cycling"
12:00-1:30 Lunch
1:30-2:00 Rob Beardmore: "Antibiotic cycling"
2:00-2:30 Andrew Read: "The in-host ecology of drug resistance"
2:30-3:30 Shigui Ruan: "Modeling Transmission Dynamics of Antibiotic- Resistant Bacteria in Hospitals"
Wednesday July 7

Fran Jamieson: "The Dark at the End of the Tunnel: The Looming Threat of Drug Resistant Tuberculosis"
Reference 1
Reference 2
Reference 3
Reference 4
Reference 5
Reference 6

10:00-10:30 Andrew Morris: "Antimicrobial Stewardship: Current Concepts and Controversies"
10:30-11:00 Break
11:00-11:30 Chris Bowman: "Transmission Dynamics of Drug-resistant Strains Driven by Treatment"
11:30-12:00 Elsa Hansen: "Optimal antiviral treatment strategies and the effects of resistance"
12:00-1:30 Lunch
1:30-2:00 Seyed Moghadas: "Within-Host Dynamics of Influenza Drug-Resistance"
2:00-2:30 Yanyu Xiao: "A modified Ross-MacDonald model with latency for malaria dynamics"
2:30 - 3:00 James Lloyd-Smith
"Disease emergence in populations with heterogeneous immunocompetence"
Thursday July 8
Teaching Session-
e.g., Introduction to estimation of R0; A Simple Model of Antimicrobial Resistance, etc
Handout 1
Handout 2
Handout 3
Handout 4
Friday July 9
9:30-10:30 Focused Discussion
10:30-11:00 Break
11:00-12:00 Focused Discussion
Week 2
Monday July 12
Research Time (4-5 resident faculty); Friday Colloquium
10:00-10:45 Vanessa Gray Allen: "Antibiotic Resistance in Gonorrhea, Chlamydia and Syphilis: Are we chasing our tail?"
1:00-1:45 Kevin Katz: "Methicillin-Resistant S. aureus"
Reference 1
Reference 2
Reference 3
Friday July 16
10:00 am Ram Laxminarayan: "Transboundary problems in infectious diseases"

Reference: Perspectives on the basic reproductive ratio

For those who attend more than two blocks of activities, see the List of Confirmed Participants of the Thematic Program.

Confirmed Participants

Full Name University/Affiliation
Alexander, Helen Queen's University
Allen, Vanessa Gray Ontario Agency for Health Protection and Promotion
Andrews, Rob (no affiliation)
Anvari, Vahid York University
Arino, Julien University of Manitoba
Beardmore, Robert Imperial College London
Beauchemin, Catherine Ryerson University
Bhattacharyya, Samit University of Guelph
Blumberg, Seth NIH Fogarty/ UCLA
Bowman, Christopher National Research Council, Institute for Biodiagnostics
Brauer, Fred University of British Columbia
Chan, Christina University of Toronto
Collinson, Shannon York University
Dai, Liman University of Western Ontario
Day, Troy Queen's University
Diekmann, Odo Utrecht University
Dobrovolny, Hana Ryerson University
Du, Yimin York University
Dushoff, Jonathan McMaster University
Edge, Tom Environment Canada
Fan, Guihong York University
Fisman, David The Hospital for Sick Children
Gandon, Sylvain Centre d'Ecologie Fonctionnelle et Evolutive
Ghosh, Suma York University
Gomero, Boloye University of Tennessee
Gourley, Stephen University of Surrey
Guo, Hongbin York University
Guo, Shangjiang Hunan University
Hansen, Elsa Queen's University
Hansen, Johanna Queen's University
Heffernan, Jane York University
Henderson, Elizabeth University of Calgary/Alberta Health Services
Holder, Ben Ryerson University
Horn, Mary Ann National Science Foundation
Hurford, Amy Queen's University
Kuster, Stefan University of Toronto
Labibi, Batool  
Li, Jia University of Alabama in Huntsville
Li, Jing University of Ottawa
Liu, Rongsong University of Wyoming
Liu, Shengqiang Harbin Institute of Technology
Lloyd-Smith, James University of California, Los Angeles
Lou, Yijun York University
Lu, Xinxin Beijing Tongren Hospital
Machalek, Karolina University of Toronto
Moghadas, Seyed University of Winnipeg
Neumann, Avidan Bar-Ilan University
Ng, Victoria University of Guelph
Pahlevani, Faranak Stevens Institute of Technology
Pawelek, Kasia Oakland University
Pena-Miller, Rafael Imperial College
Pernica, Jeff McMaster University
Pressley, Joanna Vanderbilt University
Read, Andrew Pennsylvania State University
Ruan, Shigui University of Miami
Rudnick, Wallis Mount Sinai Hospital
Sahai, Beni Cadham Provincial Laboratory & University of Winnipeg
Saini, Jasmik University of Toronto
Simmonds, Kimberley University of Calgary
Sun, Chengjun University of Manitoba
Tam, Vincent University of Houston
Taylor, Edward The Ohio State University
Toro Zapata, Hernán Dario University of Quindio
Tuite, Ashleigh University of Toronto
Vaidya, Naveen Los Alamos National Laboratory
Wan, Hui York University
Wang, Jiafeng York University
Wang, Xiaoxia Case Western Reserve University
Wang, Yan University of British Columbia
Wang, Ying The Ohio State University
Wong, Eva University of Toronto
Wu, Jianhong York University
Xiao, Yanyu University of Western Ontario
Yang, Yong York University
Zhou, Yinggao York University
Zhu, Huaiping York University
Zou, Shaofen York University

Program Visitors

All scientific events are open to the mathematical sciences community. Visitors who are interested in office space or funding are requested to apply by filling out the application form. Additional support is available (pending NSF funding) to support junior US visitors to this program. Fields scientific programs are devoted to research in the mathematical sciences, and enhanced graduate and post-doctoral training opportunities. Part of the mandate of the Institute is to broaden and enlarge the community, and to encourage the participation of women and members of visible minority groups in our scientific programs.

For additional information contact thematic(at)

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