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Seminar Series
2014-2015


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Endovascular medical procedures are becoming increasingly more common, as their minimally invasive nature allows them to be offered to patients unsuitable for conventional invasive procedures. These procedures generally involve the insertion of a medical device in the femoral artery, through the iliac artery, and into position in the aorta or further along the vasculature. Iliac arteries, especially in older patients who require such procedures, are often tortuous, calcified, and/or stenotic. Currently, the degrees of these parameters are assessed qualitatively by clinicians to decide if a particular device will go through the iliac artery and through which side it should be inserted. We propose a quantitative approach to assess tortuosity, calcification, and stenosis in iliac arteries as a first step to understanding how medical devices interact with these vessels. We aim to answer two clinical research questions a) will a device fit through an iliac artery, and b) will the device accumulate rotational energy as it moves through the iliac artery, causing it to rotate when deployed. The latter question is of particular interest for devices, such as fenestrated aortic stent grafts, which have a defined orientation, resulting in complications if rotation occurs during deployment. My presentation will focus on the methods we have proposed for quantifying iliac artery geometry and mechanical properties, the application of these methods to address clinical research questions, and our ongoing experimental and computational studies to extend these methods to real-world applications.
 
 
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