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OVERVIEW
The
brain is the most complex organ of our central nervous
system. It is responsible for controlling all the other
organs in the body, as well as breathing, heart beat and
temperature regulation. It is also the processor of all
conscious and unconscious stimuli, thought and feelings,
learning and memory. As a material, the brain is an inhomogeneous,
multi-scaled and multi-layered, inter-connected network
of neurons, glial cells, blood vessels and extracellular
matrix. The function of each of these components is interconnected
and modulated by the activity of the others. The mechanical
parameters of the brain are determined from both the constituent
elements and their electro-chemical and mechanical interactions
at all length scales.
In
recent years, a lot of progress has been made in the fields
of brain biomechanics and neuroscience. However, the two
research areas have developed independently of each other
with little cross-fertilization, neglecting any possible
linkage between the electric brain and the mechanical
brain. The lack of fundamental knowledge about the interactions
between the electrical and mechanical properties of the
brain severely inhibits the ability to interpret any neural
activity data. It also impairs the ability to intelligently
simulate the brain responses to electric and mechanic
stimuli, and impedes the development of a wide range of
feasible medical therapies.
The
objective of this workshop is to lay the foundations of
novel theoretical and computational models of the brain
that will incorporate in a common framework, knowledge about
the biomechanics and the electro-chemical processes of the
brain at different length scales. These models will have
a wide spectrum of possible applications ranging from a
more fundamental understanding mechanical deformation and
stress, to damage in a range of applications from traumatic
brain injury to hydrocephalus to electrode insertion. Ultimately
these models will help generate improved medical diagnoses,
treatment strategies and clinical protocols. Such fundamental
research will also clearly play an important role in the
design of improved experimental procedures and measurements.
List of current confirmed participants (speakers)
James
Drake, Hospital for Sick Children, Toronto,
Corina S. Drapaca, Center for Neural Engineering,
Pennsylvania State University
Patrick Drew, Center for Neural Engineering, Pennsylvania
State University,
Almut Eisentraeger, Oxford University Mathematical
Institute,
Joseph T. Francis, SUNY Downstate Medical Center,
Kristian Franze, University of Cambridge
Jurgen Germann, Toronto Centre for Phenogenomics
Bruce Gluckman, Center for Neural Engineering, Pennsylvania
State University
Paul Janmey, Institute for Medicine and Engineering,
University of Pennsylvania,
Miles Johnston, Sunnybrook Health Sciences Centre,
University of Toronto,
Leslie M. Loew, R.D. Berlin Center for Cell Analysis,
University of Connecticut Health Center
Martin Ostoja-Starzewski, University of Illinois
at Urbana-Champaign
Katerina Papoulia, University of Waterloo
Richard Penn, Neurosurgery, University of Chicago,
Andrew Sharp, Southern Illinois University School
of Medicine,
Kathleen
Wilkie,
University of Waterloo,
Alan Wineman, University of Michigan
K. P. Unnikrishnan, University of Michigan
Schedule
| Monday,
July 26, 2010 |
| 9:00
am |
Opening
Remarks |
| 9:15
am |
J.
Drake, Hospital for Sick Children |
| 10:00
am |
Miles
Johnston, Sunnybrook Health Sciences Centre, University
of Toronto, |
| 10:45
am |
Coffee
Break |
| 11:15
am |
Joseph
T. Francis, SUNY Downstate Medical Center |
| 12:00
pm |
Lunch
Break |
| 2:00
pm |
Richard
Penn, Neurosurgery, University of Chicago |
| 2:45
pm |
Corina
S. Drapaca, Center for Neural Engineering, Pennsylvania
State University |
| 3:30
pm |
Coffee
Break |
| 4:00
pm |
Kathleen
Wilkie,
University of Waterloo |
| 4:45
pm |
Jurgen
Germann, Toronto Centre for Phenogenomics |
| 5:30
pm |
Welcome
Reception |
| Tuesday,
July 27, 2010 |
| 9:00
am |
Paul
Janmey, Institute for Medicine and Engineering,
University of Pennsylvania |
| 9:45
am |
Bruce
Gluckman, Center for Neural Engineering, Pennsylvania
State University |
| 10:30
am |
Coffee
Break |
| 11:00
am |
Patrick
Drew, Center for Neural Engineering, Pennsylvania
State University |
| 11:45
am |
Lunch
Break |
| 2:00
pm |
Kristian
Franze, University of Cambridge |
| 2:45
pm |
Andrew
Sharp, Southern Illinois University School of
Medicine |
| 3:30
pm |
Coffee
Break |
| 4:00
pm |
K.
P. Unnikrishnan, University of Michigan |
| 4:45
pm |
Leslie
Loew,
R.D. Berlin Center for Cell Analysis, University of
Connecticut Health Center |
| Wednesday,
July 28, 2010 |
| 9:00
am |
Almut
Eisentrager, Oxford University Mathematical Institute |
| 9:45
am |
Alan
Wineman, University of Michigan |
| 10:30
am |
Coffee
Break |
| 11:00
am |
Martin
Ostoja-Starzewski, University
of Illinois at Urbana-Champaign |
| 11:45
am |
Katerina
Papoulia, University of Waterloo |
| 12:30
pm |
Closing
Remarks: Siv Sivaloganathan, University of
Waterloo |
List
of Confirmed Participants as of July 19, 2010:
| Full Name |
University Name |
| Bardakjian, Berj |
University of Toronto |
| Carpentier, Sarah |
Rotman Research Institute |
| Chang, Dong Eui |
University of Waterloo |
| Drake, James M. |
The Hospital for Sick Children |
| Drapaca, Corina |
Pennsylvania State University |
| Drew, Patrick J. |
Pennsylvania State University |
| Eisenträger, Almut |
Oxford University |
| Francis, Joseph T. |
SUNY Downstate Medical Center |
| Franze, Kristian |
University of Cambridge |
| Gasumova, Dana |
York University |
| Gibson, Erin |
Sunnybrook Health Sciences Centre |
| Gluckman, Bruce |
Pennsylvania State University |
| Janmey, Paul |
University of Pennsylvania |
| Johnston, Miles |
Sunnybrook Health Sciences Centre |
| Kamali Sarvestani, Iman |
Royal Institute of Technology |
| Lee, Angela |
University of Toronto |
| Loew, Leslie M. |
University of Connecticut Health Center |
| Mora, Vincent |
IMI-NRC |
| Ostoja-Starzewski, Martin |
University of Illinois at Urbana-Champaign |
| Penn, Richard |
University of Illinois at Chicago |
| Perry, Stephen |
Wilfrid Laurier University |
| Rebeira, M. |
University of Toronto |
| Shahbandi, Nazgol |
University of Waterloo |
| Sharma, Cartik |
Sunybrook Imaging Research |
| Sharp, Andrew |
Southern Illinois University School of Medicine |
| Sharp, Andrew |
Southern Illinois University School of Medicine |
| Sinclair, D.M. |
University of Toronto |
| Sivaloganathan, Sivabal |
University of Waterloo |
| Szilagyi, Gregory |
Sunnybrook Health Sciences Centre |
| Talasila, Sam |
University of Toronto |
| Unnikrishnan, K. P. |
University of Michigan Medical School |
| Wang, Hongye |
Rotman Research Institute at Baycrest |
| Wilkie, Kathleen |
University of Waterloo |
| Wineman, Alan |
University of Michigan |
| Zamyadi, Mojdeh |
Sunnybrook Health Sciences Centre |
| Zivari Piran, Hossein |
York University |
| TO BE CONFIRMED: |
| Germann, Jurgen |
Toronto Centre for Phenogenomics |
| Papoulia, Katerina |
University of Waterloo |
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