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July
27, 2007
Workshop on Brain Biomechanics: Mathematical Modelling
of Hydrocephalus and Syringomyelia
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OVERVIEW
The last two decades have witnessed an explosion in
the interactions and synergy between the mathematical
and biomedical sciences. The development of an accurate
mathematical model suitable for the simulation of the
mechanical behaviour of the human brain under different
loading scenarios will be the touchstone that may well
lead to significant advances in the clinical neurosciences.
In particular, it would lay the groundwork for model predictions
of the damage sustained by the brain in a variety of loading
conditions from hydrocephalus and syringomyelia to brain
trauma and would thus provide aid in treatment decisions.
However, such an endeavour clearly requires a multidisciplinary
approach. This workshop will focus on models of hydrocephalus
and syringomyelia and bring together leading clinician/scientists,
experimentalists and theoreticians currently engaged in
this field. The aims of the workshop are to review the
state of the field, update participants on current progress
and chart future directions.
Talks will be 20 minutes in length with an additional
5 minutes for questions/short
discussions.
Invited Participants
Registration fee for this event
is $50 CDN, $25 for students and PDF's, fee is waived
for invited participants. Registration fee will cover
on-site refreshments.
Particpants List
| Fullname |
University Name |
| Alperin, Noam |
University of Illinois at Chicago |
| Batay, Judy |
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| Chrisochoides, Nikos P. |
College of William and Mary |
| Cohen, Benjamin |
Rensselaer Polytechnic Institute |
| Drake, James M. |
The Hospital for Sick Children |
| Drapaca, Corina |
University of Waterloo |
| Egnor, Michael |
Stony Brook University |
| Ehman, Richard L. |
Mayo Clinic |
| Gunawan, Rudy |
University of Waterloo |
| Johnston, Miles |
University of Toronto
Neuroscience Research Program |
| Kazina, Colin |
University of Manitoba |
| Kohandel, Mohammad |
University of Waterloo |
| Levine, David |
NYU Medical Center |
| Madsen, Joseph R. |
Children's Hospital, Harvard Medical School |
| Margulies, Susan |
University of Pennsylvania |
| Marmarou, Anthony |
Virginia Commonwealth University |
| McAllister, James P. |
Wayne State University School of Medicine |
| Park, Eun-Hyoung |
Children's Hospital Boston, Harvard Medical School |
| Penn, Richard |
University of Chicago |
| Powathil, Gibin |
University of Waterloo |
| Rekate, Harold L. |
University of Arizona |
| Rohlf, Katrin |
Ryerson University |
| Sivaloganathan, Sivabal |
University of Waterloo |
| Speziale, Sean |
University of Waterloo |
| Stewart, Curt |
The BrainChild Foundation |
| Stinchcombe, Adam |
University of Waterloo |
| Su, Wanhua |
University of Waterloo |
| Tang, Herbert |
University of Waterloo |
| Tenti, Giuseppe |
University of Waterloo |
| Turner, Colin |
University of Waterloo |
| Wagshul, Mark |
SUNY Stony Brook |
| Walker, Marion L. |
University of Utah |
| Wang, Yanwei |
University of Waterloo |
| Wilkie, Kathleen |
University of Waterloo |
| Zamir, Mair |
Univesity of Western Ontario |
Schedule
| Thursday, July 26, 2007 |
| 7:00 p.m. |
Early Registration and
Reception |
| Friday July 27, 2007 |
| 7:30am - 8am |
Continental Breakfast |
| 7:55am - 8am |
Welcome - Jim Drake/Siv
Sivaloganathan |
| 8:00am - 8:20am |
M. Wagshul, SUNY
Stony Brook
Intracranial flow and pressure: What can we measure?
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| 8:25am - 8:45am |
R. Penn, University
of Chicago
Physics of Hydrocephalus |
| 8:50am - 9:10am |
R. Ehman,
Mayo Clinic
Magnetic Resonance Elastography by Direct MR Visualization
of Propagating Shear Waves |
| 9:15am - 9:35am |
B. Cohen, Rensselaer
Polytechnic Institute
A Mechanics-Based Framework Leading to the Diagnosis
and Treatment of Hydrocephalus |
| 9:40am - 10:00am
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N. Alperin,
University of Illinois at Chicago
"MRI based noninvasive measurement of intracranial
compliance: direct vs. modeling based approach." |
| 10:05am - 10:25am |
D. Levine, NYU
Medical Center
Intracranial Pressure in Hydrocephalus |
| 10:25am - 10:40am |
Coffee/Tea Break |
| 10:40am - 11:00am |
M. Egnor, Stony
Brook University
Modeling of Phase, Amplitude and Transfer Function
of Carotid Arterial Pulse Pressure and Intracranial
Pulse Pressure in Dogs |
| 11:00am - 11:20am |
K. Wilkie, University
of Waterloo
A Pulsatile Cerebrospinal Fluid Model for Hydrocephalus
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| 11:20am - 11:40am |
H. Rekate, University
of Arizona
All Forms Of Hydrocephalus Can Be Explained By
Derangements of Bulk Flow 30 Years of Research Driven
By A Bulk Flow Model
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| 11:50am - 12:40pm |
Panel Discussion (Theoretical
Aspects)
M. Egnor, R. Penn, D. Levine, N. Alperin |
| 12:40pm - 2:00pm |
Lunch Break |
| 2:00pm - 2:20pm |
D. Levine, NYU Medical
Center
The Syrinx as a Biological Pothole |
| 2:25pm - 2:45pm |
P. McAllister, Wayne
State University School of Medicine
Probable Cellular Influences on the Biomechanical
Properties of the Brain: The "Sponge" Changes
during Hydrocephalus |
| 2:50pm - 3:10pm |
M. Johnston, University
of Toronto
In search of mechanisms to explain ventricular
expansion in communicating hydrocephalus |
| 3:15pm - 3:35pm |
C. Drapaca, University
of Waterloo
Application of Potential Theory to MR Elastography
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| 3:40pm - 4:00pm |
S. Margulies, University
of Pennsylvania
Mechanical Properties of Brain Tissue |
| 4:00pm - 4:15pm |
Coffee/Tea Break |
| 4:20pm - 4:40pm |
A. Marmarou, Virginia
Commonwealth University
TBA |
| 4:45pm - 5:05pm |
J. Madsen, Children's
Hospital, Harvard Medical School
Intracranial pulsations and their characteristics
in hydrocephalus: inferences from the frequency domain
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| 5:10pm - 5:30pm |
N. Chrisochoides,
College of William and Mary
Near Real-Time Non-Rigid Registration of pre- and
intra-operative MRI for Image Guided Neurosurgery
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| 5:35pm - 6:30pm |
Panel Discussion (Experimental
Aspects)
P. McAllister, M. Johnston, S. Margulies, J. Madsen |
| 6:30pm - 6:35pm
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Closing Remarks
Jim/Siv |
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