April
20, 2007-- 4:00 p.m. at the Fields Institute
(audio and slides from talk) Mandar
Jog, Director, Movement Disorders Program,
London Health
Sciences Centre & Asst Professor of Clinical
Neurological Sciences, U of
Western Ontario
Thermodynamics,
entropy and information processing in the basal
ganglia
Despite
significant advances in the understanding of neurochemical
and neuroanatomical connectivity of the brain
in the healthy and disease states, we are still
no farther ahead in the understanding of how the
flow of information may be occurring within the
system. Information theory has been applied to
this system and again, in isolation has not taken
the field very far. We have used a theoretical
framework that has attempted to combine thermodynamic
and information entropy and applied it to actual
neurophysiological data from chronic multichannel
recordings from rodent basal ganglia. We have
found interesting and non-obvious results that
extend the understanding of the learning process
within the basal ganglia at a very subtle, temporo-spatial
level.
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