October 20 , 2006 -- 4:00 p.m. at the Fields Institute
(there is no audio available
for this talk) J.D.
Murray FRS, Membre de l'Insitut de France (Foreign Member,
Acad. Sci.)
Emeritus Professor, University of Oxford
Emeritus Professor, University of Washington
On the Virtues of Simple
Models in the Biomedical Sciences. The siren song of
elegant mathematical analysis often distracts
mathematicians from the most important reason for
working in the
application of mathematical models to the biomedical
sciences, namely
to further our understanding of real biomedical problems.
I shall
describe, with minimal mathematical detail, examples
ranging from
brain tumour growth and control to divorce prediction
which show how
very simple models can often provide significant insight
into real
problems in medicine and psychology. In the case of
brain tumours I
shall show, for example, how the models can enhance
imaging,
highlight problems with current medical treatments
and help design
individual patient treatment regimens. With marital
interaction
modelling I shall show how to quantify a couples
15 minute
discussion and then use it to predict marriage stability
and divorce.
We achieved a 94% accuracy based on a longitudinal
study of a large
number of newlywed couples.
WWW: http://www.amath.washington.edu/~murrayjd/
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